|
KMID : 0380020030180030222
|
|
Korean Journal of Biotechnology and Bioengineering
2003 Volume.18 No. 3 p.222 ~ p.228
|
|
|
Hydrogel Synthesis using Glycosyl Methacrylate and Acrylate: l. A Study on Chemo-Enzymatic Synthesis of Sorbitan Acrylate
|
|
Park Don-Hee
Lim Geon-Gil
Jeong Gwi-Taek
Byun Ki-Young
Kim In-Heung
Lee Gwang-Yeon
Kim Hae-Sung
|
|
|
Abstract
|
|
|
|
This study was performed to research a chemo-enzymatic synthesis of sorbitan acrylate. It w as firstly to determine the optimum conditions for D-sorbitol cyclic reaction in the presence of p-toluenesulfonic acid (p-TSA) as catalyst material. It was secondly to find the optimum conditions for sorbitan acrylate synthesis using immobilized lipase Novozym 435 in t-butanol from its materials. The maximum yield of 1,4-sorbitan synthesis were obtained approximately 90% (w/w) at 13 and 200 mmHg vacuum pressure with 1% (w/w) p-TSA after 150 min reactin time on our experimental system. The product from optimum condition was less color than those obtained at higher temperatures and minimized byproduct and unreacted D-sorbitol. Sorbitan acrylate was synthesized to around 63.5% conversion of 1,4-sorbitan. The experimental optimum condition was found at 5, atmospheric pressure, 3% (w/v) Novozym 435, 50 g/L 1,4-sorbitan of initial reactant concentration, and 1:3 molar ratio of 1,4-sorbitan to acrylic acid.D
|
|
|
KEYWORD
|
|
|
Sorbitan, chemo-enzymatic synthesis, sorbitan acrylate
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|